NKG2D expression was significantly weaker in the presence of supernatants from untreated AML cells (sNKG2DL-positive; p = 0.009 for KG1a and p = 0.002 for NB4) whilst the NKG2D expression was partially restored after incubation with DAC-treated supernatants (p = 0.023 for KG1a and p = 0.011 for NB4) (Figure 2A). The gene discussed is KLRK1; the disease is acute myeloid leukemia.