HMGB1 and hepatocellular carcinoma: To further investigate the mechanism by which TP73-AS1 regulates HCC cell proliferation, we used online tools to screen out nine miRNAs which were potentially correlated with HMGB1 (miR-200a, miR-153, miR-193b, miR-142, miR-383, miR-518a, miR-497, miR-205 and miR-141) (Fig. 3a).