There were no differences in age, sex, duration of diabetes, and baseline laboratory findings including FPG, HbA1c, eGFR, aspartate aminotransferase, alanine transaminase, HOMA-IR, and HOMA- β-Cell function between the DPP-4 inhibitor group and the SGLT2 inhibitor group. This evidence concerns the gene SLC5A2 and diabetes mellitus.