Methylation levels of the BRCA1 promoter strongly correlated with those of the CDKN2A promoter in tumors (r = 0.990, p < 0.001), tumor-adjacent tissues (r = 0.920, p < 0.001) and tumor-distant tissues (r = 0.963, p < 0.001). Here, BRCA1 is linked to neoplasm.