The I2 estimate indicated significant heterogeneity (I2 = 84%) among the studies, and the random effects model used in this meta-analysis indicated that there was no significant association between the overexpression of EpCAM and tumour stage(OR = 2.26, 95% CI: 0.79~6.45, P = 0.13; Fig 6). This evidence concerns the gene EPCAM and neoplasm.