It is well known that TP63 is critical for cell homeostasis and embryo and epidermal development.[33,34] Several studies showed the aberrant expression and structural abnormality of TP63 was found in multiple types of lymphoma.[35,36] Moreover, Fukushima et al[24] uncovered that TP63 was expressed in the nucleoli of tumor cells in 34% DLBCL, and non-germinal center DLBCL with TP63 positive displayed worse prognosis. Here, TP63 is linked to neoplasm.