CD274 and diffuse large B-cell lymphoma: The structural variation frequently disrupting the 3′ region of PD-L1 was identified in 27% adult T-cell leukemia/lymphoma and in 8% DLBCL, which resulted in the arrangement of gene's open reading frame.[19] Similarly, the PD-L1 and TP63 fusion translocation pattern was newly found in 5% (1/20) DLBCL, leading to jointly increasing the mRNA expression level of both genes.[20] Based on this intriguing finding, in this study we investigated the expression of PD-L1 and TP63 in 76 DLBCL cases by immunohistochemistry, and studied the frequency of their conjunct aberrant expressions in DLBCL.