TOMM34 is reportedly involved in the growth of cancer cells and may contribute to the development of novel anticancer drugs and diagnosis of CRCs based on the immunohistochemistry results of TOMM34 proteins in CRC tissues, which is more likely to be upregulated by amplification in CRC [20] rather than by transcriptional regulation through ATF3. The gene discussed is ATF3; the disease is colorectal carcinoma.