Jaiswal et al found that exosomes secreted by doxorubicin-resistant breast cancer cells contained abundant regulatory miRNAs (miR-451 and miR-326) and the latter conferred a more deleterious phenotype through “re-templating” recipient breast cancer cells’ transcriptional landscape to reflect the P-glycoprotein over-expressed character of donor cells [112]. The gene discussed is ABCB1; the disease is breast cancer.