Since MAOA produces H2O2 as an enzyme by-product and our results here showed that MAOA was involved in both inhibition of apoptosis and induction of autophagy in NE differentiated PCa cells, we hypothesized that ROS produced by MAOA may determine the fate of NE cells towards an anti-apoptotic and autophagy-induction state. This evidence concerns the gene MAOA and posterior cortical atrophy.