Amitava et al. showed that miR-21 functions in the resolution of wound inflammation [36], and the induction of miR-21 is associated with the silencing of phosphatase and tensin homolog on chromosome ten (PTEN) and programmed cell death 4 (PDCD4), which are tumor-suppressor genes targeted by miR-21 [36–39]. The gene discussed is PTEN; the disease is neoplasm.