IL-15 stimulation significantly increased the Tim-3+CD4+ T cells frequency in CHB patients (10.92 ± 7.92%, P = 0.008; Figure 2B) but not in AsC patients (5.85 ± 6.31%, P = 0.114; Figure 2A). The gene discussed is CD4; the disease is Tako-tsubo cardiomyopathy.