It is worth noting that both hepcidin (P = 0.17) and % saturation (P = 0.13) were 1.61x higher than controls in AD patients with CDR-SOB ranging from 6.5-12, trends that were not apparent when AD with CR-SOB score of 0-6 compared to control subjects, although neither trend reached significance. Here, HAMP is linked to Alzheimer disease.