A majority of the associated diseases and predisposing risk factors for hypercoagulable states mentioned through this literature review are pregnancy, oral contraceptives, cancer/malignancies, dehydration, infections (sinusitis), thrombophilia, and other coagulopathies (Factor V Leiden, Protein C&S deficiencies, and antithrombin III deficiency) (2,7,44). The gene discussed is SERPINC1; the disease is sinusitis.