It is used for the analysis and quantitation of 14-3-3 protein in cerebrospinal fluid (CSF) samples from cases of Creutzfeldt-Jakob disease (CJD), and for disease control of other neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) (Subramanian et al., 2016). This evidence concerns the gene YWHAQ and Parkinson disease.