CD4 and myeloid sarcoma: Multiple sclerosis (MS) in humans, and its animal model, experimental autoimmune encephalomyelitis (EAE), are characterized by demyelination in the central nervous system (CNS), as a result of inappropriate inflammation and infiltration of CD4+ T cells (Jadidi-Niaragh and Mirshafiey, 2011; Rostami and Ciric, 2013).