NOS2 and asthma: Specifically, significant associations were found in the −444A > C LTC4S polymorphism in patients with NP and atopy (p = 0.033) and NP and atopic asthma (p = 0.012); and when the CCTTT nucleotide repeat in the NOS2A gene was present >14× in patients with NP and asthma (p = 0.034), NP and NSAIDi (p = 0.009), and the aspirin triad (p = 0.005).