Furthermore, we provided the first evidence that iASPP stimulates EMT and induces cisplatin resistance in both cervical adenocarcinoma cell line HeLa and cervical squamous cell carcinoma cell line SiHa, through regulating the downstream miR-20a-FBXL5/BTG3 signaling pathway. This evidence concerns the gene FBXL5 and cervical squamous cell carcinoma.