Consistently, when the five diagnostic components of MetS were respectively set as the independent variable in linear regression analyses, central obesity (β = −0.138, P = 0.006), IFG (β = −0.113, P = 0.029), the diagnosis of MetS (β = −0.102, P = 0.045), and the count of MetS components (β = −0.169, P < 0.001) were negatively related to serum RNase-L levels after adjusting age and gender (Table 4, Model 2, 5, 7 and 8, respectively). Here, RNASEL is linked to metabolic syndrome.