Although inflammatory responses, including interferon gamma (IFN-γ), IL-12, IL-1β, IL-2, and TNF-α, play important roles that facilitate parasite clearance [9, 17, 18], circulating high levels of these cytokines have been associated with malaria immunopathology [11, 12, 14, 19–23]. The gene discussed is IL1B; the disease is malaria.