In particular, when it came to the molecular characterization proposed by TCGA [5], high level of IGF2BP3 was observed frequently in the subtype of chromosomal instability (CIN) and EBV positive GC, while its level was relative lower in genomically stable (GS) subtype (Fig. 1f). This evidence concerns the gene IGF2BP3 and cervical squamous intraepithelial neoplasia.