In a Chinese community-dwelling population, the current analysis revealed that prevalence of Mets and its components (including central obesity and high TG) increased with an elevation in serum ALT levels within normal range in both non-drinkers and drinkers, while cfPWV and other components of Mets, such as high blood pressure and glucose, increased with an elevation in serum ALT levels in non-drinkers, but not in drinkers. The gene discussed is GPT; the disease is hypertensive disorder.