Patients with diagnosis of lymphoma showed lower pre-SCT values (median, range) of naïve CD4+ (14, 1–90 vs 56, 9–205; p = 0.003), RTE (9, 0–72 vs 30, 5–94; p = 0.02), naïve Treg (1, 0–7 vs 3, 0–12; p = 0.03), CD4+TEMRA cells (40, 0–110 vs 78, 1–469; p = 0.02), and immature B cells (5, 0–32 vs 15, 0–95; p = 0.03) in comparison to other diagnosis. Here, CD4 is linked to lymphoma.