Upregulation of MMP14 and MMP16 (MT3-MMP) is involved in EMT (Gilles et al, 1997; Pulyaeva et al, 1997), and associated with the aggressiveness of human ovarian, breast and gastric cancer (Pulyaeva et al, 1997; Lowy et al, 2006; Moss et al, 2009). This evidence concerns the gene MMP14 and gastric cancer.