MiR-200 maintains ‘epithelial-ness’ by directly targeting and suppressing ZEB1 and ZEB2. Downregulation of the miR-200 family contributes to tumour metastasis (Park et al, 2008), and FN1 has been identified as a novel target of miR-200c (Howe et al, 2011). This evidence concerns the gene ZEB1 and neoplasm.