KRAS and colorectal carcinoma: Several genes associated with CRC risk have been identified, but members of the Ras superfamily, which includes the Kirsten rat sarcoma viral oncogene homolog (KRAS), Harvey rat sarcoma viral oncogene homolog (HRAS), and neuroblastoma RAS (NRAS) oncogenes, still constitute the most frequently mutated oncogenes, with a prevalence of 50% [2,3,4].