Noteworthy, expression and functional genetic polymorphisms of ABC transporters have been implicated in genetic diseases (e.g., cystic fibrosis, Stargardt disease, age-related macular degeneration, adrenoleukodystrophy, Tangier disease, Dubin-Johnson syndrome and progressive familial intrahepatic cholestasis), drug response and prognosis for numerous tumor types [2,8,49,50,51]. Here, ABCG2 is linked to neoplasm.