Our data indicate that the positive association of fractalkine with IL-1β, IL-12p70, and TNF-α may, therefore, be more consistent than its relationship with other proinflammatory cytokines including G-CSF, IFN-α2, IL-17A, and IL-6 as these cytokines were detected exclusively in T2D patients. Here, CX3CL1 is linked to type 2 diabetes mellitus.