PDHA1 and cancer: However, the results for key genes analyzed, related to glucose metabolism showed no changes in levels of lactate dehydrogenase subtype a (LDHα), pyruvate dehydrogenase alpha (PDHα), or glucose dehydrogenase (GDH; Fig. 9), which indicates that this particular effect of T1AM and its analog SG‐2 may not be the primary means by which it suppresses cancer cell proliferation, at least at the transcriptional level.