With regard to the overlapping genes, which are considered to be both miR‐146a‐5p and HCC‐related, miR‐132 might interact with RAC1, PTGS2, and NRAS via VEGF signaling pathway and mediate biological processes with SMAD4, YES1, and IQGAP1 via adherens junction. This evidence concerns the gene SMAD4 and hepatocellular carcinoma.