They did find a link between MICA mismatches and grade II–IV acute GVHD but in univariate analysis only; this link was reenforced in patients with mismatches at both MICA and HLA-DPB1 who had a significantly greater risk to develop grade II to IV acute GVHD (HR = 2.51; 95% CI: 1.30–4.87; P < 0.01). The gene discussed is HLA-DPB1; the disease is acute graft versus host disease.