Boukouaci et al. showed that the presence of anti-MICA antibodies with concomitant low serum levels of sMICA (<80 pg/mL) was associated with a lower incidence of chronic GVHD (35% when MICA antibodies positive and sMICA < 80pg/mL vs. 81% when MICA antibodies negative or borderline and sMICA > 80 pg/mL, P = 0.0004) (12). Here, MICA is linked to chronic graft versus host disease.