The representative data of FACS for basophil frequency, CD203c, and CD63+ were also shown (Figure S1 in Supplementary Material) The higher expression of CD203c on basophils correlated with disease activity, as assessed by the SLEDAI score, not only in the newly diagnosed SLE patients (Figure 1B—a) but also in the total group of patients with SLE (Figure 1B—b). This evidence concerns the gene ENPP3 and systemic lupus erythematosus.