SLC29A1 and familial pancreatic carcinoma: I3C is a small molecule (MW 147.17, well within the range of “fragments”), and Lyn-Cook and colleagues (Lyn-Cook et al., 2010; Wang et al., 2011; Paik et al., 2013) have published that I3C can enhance the sensitivity of pancreatic cancer cells to gemcitabine, possibly via upregulation of ENT1 expression (Wang et al., 2011).