Interestingly, there was a significant increase of CD133 in CSF collected from six patients with normal pressure hydrocephalus [261% ± 81.5% (SD) or 42% (SEM); p < 0.001] and six others with parkinsonism [230% ± 69% (SD) or 53%; p = 0.011]. This evidence concerns the gene PROM1 and Parkinson disease.