EGFR and non-small cell lung carcinoma: qRT-PCR assay showed higher relative miR-214 expression level in the plasma of NSCLC patients with acquired EGFR-TKI resistance than prior to EGFR-TKI therapy (5.63 ± 2.33 vs. 3.31 ± 1.24, P = 0.398) (Fig. 1a).