XRCC1 and open-angle glaucoma: At present, multiple genesand genetic loci that lead to glaucoma have been found, most of which are related toprimary open angle glaucoma (POAG) [10].There are reports that suggest an association among the hOGG1, APE1and XRCC1 genes and a susceptibility to oesophageal, breast andbladder cancer [11–13].