UNC5C and infection: The comparable number of bacteria present within infected cells at intermediate and late stages of infection (3 and 6 hpi) between UNC5C knockdown cells and control cells (S6C Fig) further demonstrates that UNC5C does not affect Shigella replication; this is in contrast with the strong increase in Shigella intracellular load in cells treated with miR-29b-2-5p (S6C Fig).