One such candidate gene for VL is GBP6. Although we consider GBP5 as a better candidate gene for PRRS response than GBP6 in the chr4:139 Mb region, the fact that GBP6 was upregulated after infection and showed evidence of ASE at all time-points post infection indicates that its cis-eQTL may respond to viral infection. This evidence concerns the gene MLC1 and viral infectious disease.