39 have reported low levels of SGK1 expression in patients with miscarriages and its inverse correlation with miR‐199b‐5p. This suggests that there are likely to be other miRNAs that are involved in the down‐regulation of SGK1. Previous studies have demonstrated that SGK1 regulates cell survival, proliferation and differentiation through MDM2 or p53 40, 41. This evidence concerns the gene TP53 and spontaneous abortion.