Although CDH1 is key for the maintenance of epithelial stem cells [5, 7, 80], many reports reveal that CDH1 loss is associated with EMT [81, 82], a cancer stem cell-like behavior [39], and its deficiency is characteristic of invasive breast lobular carcinomas, especially in TNBC [36, 37]. This evidence concerns the gene CDH1 and invasive lobular breast carcinoma.