SMAD4 and colorectal carcinoma: Alone or in combination with SMAD4, miR-224 could be an independent prognostic marker for the survival of CRC patients [62, 63 MVc contains miR-155, an oncogenic microRNA that is significantly up-regulated by coculture with LC-MSCs and by S100A4 ectopic overexpression [39] (Table 1).