For this purpose, the tissue expression of the following lncRNAs were used: the long non-coding RNA HOX-class I homebox genes-transcript antisense intergenic RNA (HOTAIR), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), lncRNA- high expression in HCC (HEIH), TUC338, TUC339, maternally expressed gene-3 12 (MEG3 12), anti-differentiation ncRNA (ANCR) and highly up-regulated in liver cancer (HULC). This evidence concerns the gene HULC and hepatocellular carcinoma.