STX2 and hemolytic-uremic syndrome: Multivariable analyses independent of serotype, when adjusted for age group and presence of Stx, confirmed age ≤5 years (aOR 12.7, 95% CI; 4.2–39), stx2a (aOR 28.6, 95% CI; 12.7–158) and the virulence gene nleH1–2 (aOR 8.4, 95% CI; 2.18–32.3) as independent risk factors for the development of HUS (Table 2).