POT is a moderately vascularized tumor, in which there is greater vascular density and vascular neoformation in the mesenchyme located just below the epithelium, an area that also shows greater expression of Syndecan 1, CD 34, Ki-67 and Glut-1, indicating that this is the area with the greatest proliferative activity and in which the necessary elements for the development of the tumor converge. This evidence concerns the gene SLC2A1 and neoplasm.