Interestingly, it would require intervention studies to understand if some natural molecules can counteract the hormonal and pro oncogenic effects of endocrine disruptors as recently seen for curcumin, a bioactive anti-inflammatory compound that has shown interesting protective properties against cancer proliferative effects of bisphenol a trough its modulation of miR-19/PTEN/AKT/p53 axis [68]. The gene discussed is AKT1; the disease is cancer.