DAPK1 and urinary bladder cancer: In this study, we have shown that DAPK1 was downregulated in bladder cancer with high T-stage in 4 independent bladder cancer patient cohorts (n = 743), each with more than 130 patient specimens, and a low level expression of DAPK1 was correlated with poor prognosis in 3 independent bladder cancer patient cohorts with patient survival status available (n = 462).