MTOR and epilepsy: This is consistent with that mTOR signaling pathway plays a role in RE physiopathology[83]; Module M37 was another significant network module because its most important function was oxidative phosphorylation—a function that was crucial for the development of epilepsy[84]; In our previous studies[23], four proteins (MT-CYB, UQCRB, UQCRC1 and UQCRH) were identified to be potential drug targets for RE.