Besides leprosy, for which a clear link to CD susceptibility genes like NOD2 [30] and IL23R [31] has been established, the microsatellite polymorphism in TLR2 has been associated with further infectious conditions linked to CD-associated NOD2 variants, like the susceptibility to develop spontaneous bacterial peritonitis in liver cirrhosis [15, 16]. This evidence concerns the gene IL23R and leprosy.