There was also a significant accumulation of CD45+CD3− cells in the TME (TT- 2.8 ± 1.1%) compared with non-cancerous tissue (NT- 0.6 ± 0.4%); these cells could be of myeloid origin including granulocytic myeloid-derived suppressor cell(s) (G-MDSC) and neutrophils, which suppress host immune responses against cancer and hence promote cancer progression. This evidence concerns the gene PTPRC and cancer.