GPT and tuberculosis: The results of the present study demonstrated that administration of the anti-TB drug (INH 50 mg/kg, RIF 250 mg/kg, and PZA 100 mg/kg, p.o.)could induce a significant liver injury, as evidenced by the elevation of serum ALT, AST, AKP, and TBIL levels, nuclear pleomorphism, and liver pathological changes.