AURKA and neoplasm: Interestingly, from these 17 significant pairs (adjusted p-value ≤ 0.05) several downregulated tumour-suppressor miRNAs (e.g., miR-let-7c, miR-139, miR-145 or miR-195) appeared to regulate oncogenic genes related to the cell cycle and DDR pathways (BUB1B, AURKA, BIRC5, CENPK, BRCA1 and CHEK1).