KCNMA1 and essential hypertension: To our knowledge, there is only two reported cases of KCNMA1 variants; first study, Tomas M et al. 24, when he reported a relation between KCNMA1 and severe essential hypertension and myocardial infarction24, second, Du W et al. 25, when they reported that KCNMA1 mutation would result in generalized epilepsy and paroxysmal dyskinesia25.