A total of 14 cancer genes with an OncoScore above the 90th percentile was identified (ETV6, TNFRSF1A, ING4, CDKN1B, MIR200C, LTBR, FOXM1, GPRC5A, KDM5A, TIGAR, PRB2, CCND2, RAD51AP1 and KLRK1; OncoScore range: 59.1–86.7). The gene discussed is TIGAR; the disease is cancer.